skylarking and Administration of drugs: requires individual dosage regimen, the usual dose for adults, the recommended dose for sedation for adult patients under 60 years was 0.07 - 0.08 mg / kg / m and injected about 1 h before surgery intervention, this should individualize the dose-particular reducing the patients with XP. For children the recommended dose for sedation prior to or during diagnostic procedures in combination with local anesthesia or without it: / v - age 6 months to 5 years: initial dose - 0,05 - 0,1 mg / kg, total dose - less than 6 mg from age 6 to 12 years: skylarking dose - 0,025 - 0,05 mg / kg, total dose - less than 10 mg rectally to children older than 6 months: 0,3-0,5 mg / kg in / m for children aged 1 to 15 years: 0,05-0,15 mg / kg for premedication: rectal children older than 6 months - 0,3-0,5 mg / kg, m children aged 1 to 1915 - 0,08-0,2 mg / kg for introduction to anesthesia and sedation in intensive care: in / in newborn gestational age 32 weeks to -0.03 mg / kg / hr., newborns aged between 32 weeks to 6 months Traction 0.06 mg / kg / hr., in / in age from 6 months - loading dose 0,05-0,2 mg / kg skylarking dose - 0,06 - 0,12 mg / kg / hr. Side effects and complications in the skylarking of drugs: after / v input - Apnea; locally after i / v injection - pain during injection, phlebitis and skin redness, dry mouth, hiccups, nausea, vomiting, headache, drowsiness, weakness, retrograde amnesia, delirium after withdrawal from prolonged anesthesia and out of the anesthesia, isolated cases of AR (skin rash, urticaria, angioedema), bradycardia, chest pain, decreased cardiac output, stroke volume and systemic vascular resistance, visual disorders, jaundice, dyskraziya blood, urine retention, incontinence, change in libido, the development of dependence is generated skylarking the application, even short term use in therapeutic doses, especially in patients with alcohol or drug addiction or a history of pronounced personality disorders; cancellation drug may be accompanied with-s or cancel IOM IOM-rebound, including anxiety, depression, impaired concentration of attention, insomnia, headache, dizziness, tinnitus, loss of appetite, tremors, increased sweating, irritability, violation of perception (hypersensitivity to physical, visual and audio stimuli, changing the taste), nausea, vomiting, abdominal cramps, heart palpitations, mild systolic hypertension, tachycardia and orthostatic hypotension. Derivatives of benzodiazepines. Method of production of drugs: Mr injection of 2 ml, 5 ml, 10 ml vial. The main pharmaco-therapeutic effects: a means of anesthesia with moderate activity and a large spectrum of therapeutic action. Indications for use drugs: for sedation, including during the short-term manipulation and during surgical operations, skylarking the introduction of anesthesia and its support, sedation during intensive care in complex anticonvulsant therapy as well as in other cases when the required destination drugs with short duration group benzodiazepines. Pharmacotherapeutic group: N01VA02 - preparations for local anesthesia. Pharmacotherapeutic group: N05CD08 - hypnotic and sedative drugs.
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